What started off several months ago as just fatigue and tiredness in his legs which would go away while sitting or sleeping, has now turned into severe pain in his legs (from his waist down to his ankles) which is constantly with him. It is bearable pain when sitting or laying down but quickly becomes unbearable when standing or walking. This major change happened approx. 10 weeks ago and the only thing that we can figure to explain this change was a missed step coming down the stairs which resulted in a loss of balance and awkward recovery that twisted the back and seemed to hurt something internal to the spine area. Have since had an X-ray and MRI which continues to show the formerly diagnosed spondylolisthesis. This diagnosis has now been discounted by Dr. Quigley (Spine specialist) as the source of the severe pain in the legs. Dr. Quigley feels that "spondy.." is not the likely source of the pain and that further testing is required to make a more accurate diagnosis. While we wait to figure out the root cause of the issue, dad's pain seems to be uncontrollable resulting in him being extremely restless. In order to control the pain have tried the following since 3/19/10: - 3 epidural shots in the back with the last one administered on 5/1/10. There was no relief at all from these shots - Oxycodone (10 - 325mg) - 1 tablet every 6 hours (Hit or Miss Relief) - Fentanyl 25mcg Pain Patch - replace every 72 hours - Prescription given on 4/1/10 to replace ineffective Oxycodone. Once again Hit or Miss relief. - Lyrica (50mg) - prescribed on 4/6/10 by Dr. Loev Overall medical history: - No history of vascular/muscular pain in the past - No history of arthritis - No history of heart disease or diabetes - No medicines taken on a regular basis Chronology of treatment (prior to onset of excruciating pain): - Primary care physician Dr. Anoma Bandara referred dad to a vascular specialist Dr. Robert Fox (Jan 2010) - Dr. Fox did a sonogram and found no vascular issues and requested MRI's of the spine (results and images on CD) and referred dad to see Dr. Quigley (Orthopedic surgeon) - completed in Feb 2010 - Meanwhile Dr. Bandara reviewed the MRI report and referred dad to see Dr. Zachary Levine a neuro surgeon from the Brain and Spine institute - Dr. Levine asked for an X-Ray to be done (results and images on CD) and recommended against any kind of surgery based on Dad's age and instead recommended physical therapy. - completed in Feb. 2010 -In order to pursue possible parallel diagnosis of the issue also saw Dr. Quigley (spine specialist) who prescribed some steroids to attack possible inflammation in the spine area and possibly relieve the pain. He diagnosed the condition as "Isthmic Spondylolisthesis". After a weeks worth of taking the medicine there was no improvement. Dr. Quigley then recommended injections directly in the spine to possibly provide relief. Since the conditions worsened: 3/19/10 to present - 3 epidural shots to the back - Medications listed above all prescribed after the onset of the intense pain - Another X-Ray and MRI of the back which still shows the spondylolisthesis at L5-S1 - Met with Dr. Quigley (spine specialist) again and he no longer feels that the pain in the legs is caused by the spondylolisthesis seen in the back based on the fact that there has been no relief from the 3 epidural shots that were administered. - Also performed the following tests - full body bone scan (showed no problems) - nerve conduction study and EMG (showed some erratic nerve issues at the L5-S1 vertebrae which confimred what was seen in the MRI) - An array of blood work (everything was fine) -Saw a different vascular surgeon and repeated the ultrasound test which showed no vascular problems -Saw a rheumatologist who also confirmed that there were no signs of arthritis -Saw a different neurosurgeon who asked us to pursue with a neurologist to determine the source of the pain. -Currently waiting to see a neurologist for follow up -Currently undergoing physical therapy to basically stretch the muscles and provide some heat -Also currently undergoing aqua therapy in a pool to help get the legs moving -Have also had 4 appointments with a licensed acupuncturist -None of the above therapies have provided any relief and the conditions with the leg pain are still the same