Hirschsprung's disease, or congenital aganglionic megacolon, involves an enlargement of the colon, caused by bowel obstruction resulting from an aganglionic section of bowel (the normal enteric nerves are absent) that starts at the anus and progresses upwards. The length of bowel that is affected varies but seldom stretches for more than a foot or so. What I need to know about Hirschsprung's Disease On this page: What is Hirschsprung's disease? Why does HD cause constipation? What causes HD? If I have more children, will they have HD too? What are the symptoms? How does the doctor find out if HD is the problem? What is the treatment? What will my child's life be like after surgery? Points to Remember Glossary For More Information Acknowledgments What is Hirschsprung's disease? disease of the large intestine. medical suppy can be very exspensive and medical does not cover most of his supplies looking to find help with medical supplies please